Oral Levetiracetam Side Effects: Managing Their Impact

Oral Levetiracetam Side Effects: Strategies for Managing Them

Levetiracetam oral tablets and extended-release (ER) oral tablets are generic drugs commonly prescribed for certain types of seizures in adults and some children. These drugs are available under the brand names Keppra and Keppra XR, respectively.

While Levetiracetam is an effective treatment for seizures, it can cause common side effects such as sleepiness, irritability, aggression, weakness, dizziness, fatigue, nasal congestion, and low appetite. Mild side effects are usually manageable, but if they persist or worsen, it's essential to discuss them with your doctor or pharmacist. They can help you manage these side effects or explore alternative treatment options.

Though rare, an allergic reaction to Levetiracetam can occur. Symptoms of an allergic reaction can range from mild, such as a rash or itching, to severe, including swelling or difficulty breathing. If you experience a mild allergic reaction, contact your doctor immediately. For severe reactions, seek emergency medical help by calling 911 or your local emergency number right away.

It's crucial to be aware of any pre-existing allergies before taking Levetiracetam. People with hypersensitivity reactions to the active substance or excipients, including skin reactions like rash, itching, eczema, and other hypersensitivity manifestations, are at risk of severe allergic reactions.

Levetiracetam can also cause severe skin reactions, including Stevens-Johnson syndrome, toxic epidermal necrolysis (TEN), and drug rash with eosinophilia and systemic symptoms (DRESS syndrome). If you suspect you have developed such a reaction, contact your doctor immediately.

New or worsening depression was a common side effect reported in clinical trials of Levetiracetam oral tablets and ER oral tablets. If you experience symptoms of depression, such as unusual changes in mood, loss of pleasure in activities that usually bring you joy, and suicidal thoughts or behaviors, it's essential to talk with your doctor.

Long-term side effects weren't reported in clinical trials of Levetiracetam oral tablet and ER oral tablet. Levetiracetam is meant to be a long-term treatment, and taking the drug long term isn't expected to increase your risk of side effects.

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Before taking Levetiracetam, discuss your health history with your doctor, including mental health conditions, kidney problems, previous allergic reactions to this or a similar drug, pregnancy, breastfeeding, alcohol consumption, and any other relevant factors. If you develop serious side effects while taking Levetiracetam, call your doctor right away. If the side effects seem life-threatening or you think you're having a medical emergency, immediately call 911 or your local emergency number.

If you want to report a side effect while taking Levetiracetam, you can visit MedWatch or call 800-FDA-1088.